Ready To Use in Liquid Form

ITbio-PDNVs™ are nano-sized vesicles isolated from Italian Organic agriculture-derived fruit and vegetables. PDNVs are purified and concentrated in sterile condition, in order to render them suitable for in vitro and in vivo assays. They are provided in vials containing 2×1010 vesicles suspended in sterile water. 



Ready to use in lyophilized form

ITbio-PDNVs™ in lyophilized form are manufactured through freeze-drying process in order to increase the shelf life of nanovesicles, without altering the physico-chemical characteristics of the PDNVs. Each vial contains 2×1010 vesicles that can be stored at either -20°C or -80°C for the best costumer use.




Our research team can offer two options to the costumers. PDNVs, always from fruits and vegetables provided from Italian organic agriculture, either free from additional molecules (ready to use) or loaded with a desired molecule according to the costumer’s request.

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Our Technology

Plant Nanovesicles

Plant nanovesicles are nanometer in size and are carriers of molecules essential to life including proteins, bioactives, lipids, and nucleic acids.

  • Our technology is based exclusively on physical methods of separation (i.e. without the use of either chemical or alcoholic extractions), keeping the preparation intact and immediately bioavailable. Using this method we have shown that the Nanovesicles purified and concentrated from fruits and vegetables from organic agriculture have a potent antioxidant activity, which does not derive from a sort of pooling of individual antioxidants (eg ascorbic acid, glutathione, catalase), but from their functional aggregation inside a phytocomplex that is naturally formed within the vegetables with the purpose to multiply the function as compared to the single bioactives.


About exolab

We are pioneers, with more than 20 years of research, in the innovative use of Extracellular Vesicles (EVs).

In the last 5 years we have dedicated our research on nanovesicles (PDNVs) derived from typical Italian organic agriculture vegetables.

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We provide plant-derived nanovesicles preparations available for the use of both companies and research centers involved in pre-clinical research.

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